Metformin Side Effects: Uses, Common, Severe, Long Term

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Metformin Side Effects – Metformin is used to treat elevated glucose levels that are brought on by a sort of diabetes mellitus or sugar diabetes called type 2 diabetes. With this kind of diabetes, insulin created by the pancreas is unable to get sugar into the cells of the body where it can work correctly. Using metformin alone, with a sort of oral antidiabetic medicine called a sulfonylurea, or with insulin, helps to reduce blood sugar when it’s too high and help restore how you use food to generate energy.

Following a specially planned diet and exercise will always be important once you have diabetes, even if you’re taking medications. To operate correctly, the quantity of metformin you take must be balanced against the amount and kind of food you consume and the quantity of exercise that you do. Should you change your diet or workout, you are going to want to check your blood sugar to learn whether it’s too low. Your health care provider will teach you exactly what to do if this really occurs. Metformin doesn’t help patients who’ve insulin-dependent or type 1 diabetes because they can’t produce insulin from their pancreas gland. Their blood sugar is best controlled by insulin injections.


Metformin Side Effects

Metformin causes some frequent side effects. These may happen when you first begin taking metformin but generally, go away as time passes. Tell your doctor if any of these symptoms are severe or cause an issue for you.

Nausea, nausea, gut upset, nausea, weakness, or a metallic flavor from the mouth might happen. If any of these effects persist or worsen, then tell your health care provider or pharmacist immediately. If gut symptoms return after (after taking the identical dose for many days or months ), tell your health care provider straight away. Stomach symptoms that occur following the very first days of your therapy may be indications of lactic acidosis.

A lot of people using this medication don’t have severe side effects. Metformin does not ordinarily induce low blood glucose (hypoglycemia). Low blood glucose might happen if this medication is prescribed along with other diabetes medicines. Speak to your health care provider or pharmacist about whether the dose of another diabetes medicine (s) must be reduced. Symptoms of low blood glucose include abrupt perspiration, vibration, quick heartbeat, suspended er.


  • Abdominal or stomach discomfort
  • cough or hoarseness
  • decreased appetite
  • diarrhea
  • fast or shallow breathing
  • fever or chills
  • the general feeling of discomfort
  • lower back or side pain
  • muscle pain or cramping
  • painful or difficult urination
  • sleepiness



Many health care providers prescribe metformin since it helps reduce your glucose levels after meals (postprandial blood glucose ) and your own body’s baseline blood glucose levels (basal blood glucose ). Both these dimensions are important in regard to handling prediabetes and type two diabetes and maintaining blood sugar in check.

Metformin Precautions

Before choosing this medicine, tell your health care provider or pharmacist if you’re allergic to metformin; even in the case, you have some other allergies. This item could contain inactive ingredients, which may lead to allergic reactions or other issues. Speak with your pharmacist for additional information. Before using this medicine, tell your physician or pharmacist your medical history, especially of: acute breathing issues (for instance, obstructive lung disorder, acute asthma), blood issues (for instance, nausea, vitamin B12 deficiency), kidney disorder, liver disorder. Before having surgery or some other X-ray/scanning process with iodinated contrast, tell your health care provider or physician about all of the products that you use (such as prescription medications, nonprescription medications, and herbal products).

You might want to stop this medicine for a brief time for your surgery/procedure. Consult your health care provider or dentist for directions before your surgery/procedure. You will experience blurry vision, nausea, or drowsiness due to extremely low or higher blood glucose. Don’t drive, use machines, or perform any activity that needs alertness or apparent eyesight until you’re confident that you can perform such tasks safely. Restrict alcohol while using this medicine since it can boost your chance of lactic acidosis and growing low blood glucose. Stop taking this medicine and tell your physician straight away in the event that you have protracted nausea or nausea. It could be more difficult to restrain your blood glucose as soon as your body is stressed (like because of fever, disease, trauma, or operation ).

Seek advice from your physician because increased anxiety may want a change in your treatment program, drugs blood or blood glucose testing. Older adults may be at higher risk for side effects like low blood glucose or lactic acidosis. Your physician may direct you to utilize insulin rather than the product through your pregnancy. Follow your physician’s instructions carefully. Metformin can cause fluctuations in the menstrual cycle (encourage ovulation) and raise the danger of getting pregnant. Ask your physician or pharmacist regarding using reliable birth control whilst using this medicine. Metformin passes into breastfeeding milk in tiny quantities. Ask your physician prior to breast-feeding.

Metformin interactions

Medication interactions may alter the way your drugs operate or increase your risk for severe side effects. This record doesn’t include all potential drug interactions. Maintain a listing of all of the products that you use (such as prescription/nonprescription medications and herbal remedies ) and discuss it with your health care provider and pharmacist. Don’t start, stop, or change the dose of any medications without your doctor’s approval.

Additional symptoms of low blood glucose, for example, nausea, appetite, or perspiration, are unaffected by those medications. Many medications can influence your blood glucose, which makes it more challenging to control. Prior to starting, stop, or alter any medicine, speak to your physician or pharmacist about the way in which the medication might impact your blood sugar. Assess your blood glucose frequently as directed and discuss the outcomes with your physician. Tell your health care provider straight away in the event that you have signs of elevated or low blood glucose. Your physician might have to modify your diabetes medicine, exercise plan, or diet plan.

Metformin Overdose

Metformin is commonly used in the treatment of type 2 diabetes mellitus (DM). Severe lactic acidosis is a rare side effect of this drug. We present a 45-year-old man who deliberately took 30 g of metformin, presumably with suicidal intent. He had not eaten the previous night and presented with altered sensorium and recurrent seizures. He had profound metabolic acidosis at presentation with a pH of 7.06 and a low blood sugar of 44 mgs/dl. The patient was admitted in intensive care unit (ICU) with the suspicion of metformin-associated lactic acidosis. He developed irreversible renal failure, neurological deterioration and anemia. Despite of daily intensive hemodialysis and other supportive measures the patient expired 14 days later. Metformin overdose with renal failure and severe lactic acidosis have high mortality; hence, urgent medical consultation and treatment can be life saving in these patients.


How to Take Metformin

The metformin dose your doctor prescribes depends on many elements. These include: That the type and severity of the illness you are using metformin to deal with your era the Kind of metformin you choose other medical conditions you might have They will finally prescribe the smallest dose that offers the desired result. This information describes dosages which are generally used or advocated. But, make sure you spend the dose your physician prescribes for you. Your health care provider will decide the ideal dose to fit your requirements.